The FTSE 100 is down 24.8 points, or 0.38%, to 6,540.6 in early trading, as broker downgrades and poor miners are weighing on the index.
Early struggles on the FTSE 100 continued throughout the day as the index finished down 51 points, or 0.77%, on 6565.4.
Early struggles on the FTSE 100 have seen it slump 33.7 points, or 0.51%, to 6582.70 in early trading.
The FTSE 100 has ended the day up 9.8 points, or 0.15%, to 6,616.4, although Tate & Lyle limited any substantial gains.
The FTSE 100 is up 16.2 points, or 0.25%, to 6,622.8 in early trading, as an increased demand for utilities is pushing the index higher.
The FTSE 100 has ended the day down 30.2 points, or 0.46% to 6,606.6, as gains by financial stocks were offset by disappointing trading results.
The FTSE 100 is down 16.9 points, or 0.25%, to 6,619.9 in early trading, as suggestions a diabetes drug produced by GlaxoSmithKline increases the risk of heart attacks.
The FTSE 100 has ended the session down 4.1 points, or 0.06%, to 6,636.8, despite a rally from the mining sector following positive broker comment.
The FTSE 100 is slightly down in early trading with a fall of 0.7 points, or 0.01% to 6,640.2, despite a rise in the mining sector.
The FTSE 100 has ended the session up 61.6 points, or 0.94%, to 6,640.9, as mining and oil stocks pushed the index well above 6,600.