The FTSE 100 has ended the day down 53.3 points, or 0.81%, to 6,550.4, as miners declined on falling metal prices.
The FTSE 100 is down 27.9 points, or 0.42%, to 6,575.8 in early trading, ahead of this week's interest rate decision by the Monetary Policy Committee.
The FTSE 100 crossed the 6,600 barrier as it ended the session up 65.9 points, or 1.01%, to 6,603.7, on continued takeover rumours.
The FTSE 100 is up 22 points, or 0.34%, to 6,559.8 in early trading, as the mining sector pushes the index higher on rising commodity prices.
Head start: The twists and turns in Japan's economy have made stock picking difficult. But there are still investment opportunities to be had. Jo Tura finds out where they are...
The FTSE 100 has ended the day up 53.3 points, or 0.82%, to 6,537.8, as strong results news pushed the index through the 6,500 barrier.
In early trading the FTSE 100 is up 39.4 points, or 0.61%, to 6,523.9, with Prudential leading the gains.
A metal producer helped push the FTSE 100 towards a promising end-of-day total, the index finishing up 65.5 points, or 1.02%, to finish on 6485.1.
The FTSE 100 is up 54.9 points, or 0.86%, to 6,474.5 in early trading, as miners and property stocks push the index higher.
The FTSE 100 has ended the day down 29.6 points, or 0.46%, to 6,419.6, as the index failed to build on gains by media and communication stocks.