Barclays' head of compliance Sir Hector Sants will not be returning to the banking group after taking three months' leave in October due to stress.
Sants (pictured) was brought in to Barclays last year, tasked with setting up a group-wide compliance function.
His leave was supposed to span the last quarter of the year, and he planned to return to his role in the new year.
However, the head of compliance decided to resign from his position permanently, saying he will not be able to return to work in the near term.
Before joining Barclays, Sants was chief executive of the Financial Services Authority. He took leave from his role in Barclays after less than a year, having started the job in January.
Reports suggest one of the reasons for his leave was the bank's recent £5.8bn rights issue, after it was forced to raise fresh capital due to regulatory pressures.
Barclays suspended several of its currency traders this month as part of an internal investigation into alleged price fixing within currency markets.
Last year the bank was fined £290m for its role in LIBOR rigging. It has also had to set aside a large pool of money, along with other high street lenders, to cover claims of mis-sold PPI.
Shaygan Kheradpir, chief operations and technology officer at the bank, is also leaving the group to take on a role as CEO of a US-based company.
100 new clients
Achievements, charity work and other happy snippets
Square Mile’s series of informal interviews
Partner Insight: The rise in demand for DFM and multi manager solutions has been largely driven by new mandates from the regulator, says James Bampton, head of UK intermediary distribution at Architas