The Dow Jones opened more than 20 points lower Friday after AIG posted a $9bn Q4 loss.
Despite positive economic news - US GDP grew by 5.9% in the final three months of last year, better than forecast - the index opened at 10,342.65, down 21.62 points, or 0.21%.
AIG reported a bigger-than-expected $9bn quarterly loss in Q4, following two quarters of profits. The insurer lost $62.6bn last year.
JP Morgan Chase headed up the winner's chart, trading at $41.67, up 1.03 points, or 2.53%.
The bank was buoyed by executives' plans, outlined yesterday, to double net income from last year's $11.7bn.
Coca Cola lost more than 1% following news it will acquire the North American bottling business of Coca-Cola Enterprises Inc in a deal valued at $13bn.
In London, the FTSE approached close at 5,338.37, up 60.15 points (1.14%) on positive US economic news.
Serco gained almost 6.5% to trade at 555p while Anglo American and Vedanta Resources added 2.75% and 3.45% respectively.
Lloyds Banking Group lost 4.57% while RBS, fresh from announcing a £3.6bn annual loss, dropped 1.72% to 37p.
Two global vehicles
'Further plug advice gap'
Must appoint separate CEOs and boards
Advisers do come out well
Will report to Mark Till