The FTSE 100 is down 24.8 points, or 0.38%, to 6,540.6 in early trading, as broker downgrades and poor miners are weighing on the index.
Pub and restaurant firm Mitchells & Butler is the biggest loser with a fall of 2.34% to 854.5p, following a broker downgrade over worries about delays to its plans to improve the capital structure, while Lonmin has fallen 1.37% to £38.03.
Land Securities is also down 1.48% to £18.65, closely followed by Home Retail which has slipped 1.27% to 466.25p, while ICAP fell 1.24% to 517.25p, although losses are being limited by Legal & General which is up 0.45% to 154.6p.
However, Experian is posting the biggest gains with a rise of 0.98% to 616.5p, closely followed by cruise operator Carnival which has added 0.79% to £25.66, while British Airways has advanced 0.66% to 460.5p, and Aviva has climbed 0.56% to 802p.
In Japan, the Nikkei 225 Stock Average slid 215.76, or 1.2%, to 17,481.21 at the 3pm close, as exporters paced losses on concerns the US Federal Reserve will lift interest rates.
Canon dropped 140 yen, or 2%, to 6,980, while Toyota slid 110 yen, or 1.5%, to 7,280, and Sony fell 90 yen, or 1.3%, to 6,860, as the yen rose as high as 120.85 per dollar in New York.
Elsewhere, Mizuho, Japan's second biggest lender by assets, fell 9,000 yen, or 1.1%, to 843,000, while Mitsubishi UFJ Financial Group, the nation's biggest, dropped 30,000 yen, or 2.1%, to 1.38 million.
In the US, the Dow Jones Industrial Average fell 84.52 points, or 0.62%, to 13,441.13, over concerns interest rates won’t fall in the near future.
Intel was the biggest loser with a fall of 3.09% to $21.97, closely followed by General Motors which slipped 3.05% to $30.47, while Disney fell 1.75% to $35.84, and IBM dropped 1.54% to $103.95.
Du Pont was down 1.48% to $51.34, although losses were limited by American Express which advanced 0.05% to $63.02, while Johnson & Johnson climbed 0.13% to end at $63.48.
However, Boeing posted the biggest gains with a rise of 1.94% to $97.42, closely followed by Wal-Mart which added 0.69% to $46.65, while Home Depot rose 0.44% to $38.95.
To make any comments on this story contact:
Tel: 0207 034 2681
Email: [email protected]
Two global vehicles
'Further plug advice gap'
Must appoint separate CEOs and boards
Advisers do come out well
Will report to Mark Till