The FTSE 100 fell 8.40 points, or 0.1%, to 6,081 points today, led by a slump by mining companies at the end of the session.
Antofagasta fell 2.57% to 2,348p, Anglo American dropped 2.73% to 2,386p, Kazakhmys slumped 3.10% to 1,188p and Rio Tinto was 3.70% lower at 3,075p.
Prudential said sales climbed a better than expected 27% during the first quarter following a big performance from the Asian business, but its shares ended 0.52% lower at 665p.
Meanwhile, Barclays gained 0.07% to 677p after Morgan Stanley upped its price target to 850p from 740p and stuck with its "overweight" advice on the bank.
ICI rose 2.34% to 371.25p on the back of results from European peer Akzo Nobel, which beat forecasts by posting first quarter profit before interest and tax of €375m.
And Yell gained 3.34% to 541.50p on talk it will pay Spain’s Telefonica less than expected for yellow pages group TPI.
In the US, the Dow Jones Industrial Average has risen 38.66 points, or 0.3%, to 11,317.43 points after profit reports from General Motors and Merck topped analysts' expectations.
GM has jumped $1.87, or 9.1%, to $22.44 for the best gain in the Dow average and the stock's top performance since May 2005.
Excluding some costs, GM's first-quarter profit was 26 cents a share, compared with the analyst estimate for a loss of 44 cents in a Thomson Financial survey.
Merck has gained 27 cents to $34.67. The company says first-quarter profit rose 11% to $1.52bn on sales of the Zocor cholesterol drug, the Singulair allergy pill and vaccines.
EBay has fallen $3.39, or 8.4%, to $36.96 after it said sales this year may be as much as $5.9bn, below the $5.96bn estimated by analysts in a Thomson survey.IFAonline
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