Miners relinquished some of yesterday's gains in early trading on Thursday, pulling the FTSE more than 20 points lower to 5,659.
Antofagasta fell 2.7% to £12.78 while Xstrata slipped 1.2% to £12.71 as miners reversed gains built on rising metal prices.
Kazakhmys fell 2.8% to £14.41 and revealed it would be selling 9.4 million shares previously owned by Vladimir Ni, a non-executive director who recently died.
Elsewhere, Marks & Spencer reported a 5.3% jump in sales in the 13 weeks to 2 October, compared to analyst expectations of 3.6%, but its shares still fell 1.4% to 385.2p.
African Barrick Gold advanced 0.5% to 641p on robust metal prices.
In the US, the Dow Jones climbed 0.2% to 10,967.65 despite a disappointing jobs report stating employers cut 39,000 jobs last month.
Motorola fell 0.9% after suggesting it might spin off its mobile phone business, while Verizon rose 0.8% to $33.36 on reports it plans to sell Apple's iPhone from next year.
In Asia, Tokyo's Nikkei 225 was broadly flat at 9,684.81.
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