London trading got off to a shaky start this morning after the Fed warned of a fragile recovery in the US.
The FTSE opened down 9.88 points, or 0.19%, to 5,300.78, with financials worst hit.
RBS shares fell 2.33% to 32.23p per share in early trading, while Barclays dropped 1.7% to 292p.
Miners Xstrata were among the biggest losers, down 1.49% to £10.56 per share.
Supermarket giant Tesco saw its shares slip 1.5% to 429.10p on news of lacklustre sales figures.
Like-for-like sales rose just 2.8% in the three months to November, slightly below expectations of a 3% increase, as the group battles with stagnant food price inflation.
Across Europe banks suffered on the news from the Fed pointing to a continuation of low interest rates and a fragile recovery for the world's biggest economy.
In France the Cac 40 was held back by suffering financials, opening 0.32% lower at 3,827.58.
US markets showed little reaction to Bernanke's speech. Early gains on Wall Street following his comments had pegged back by the close and the Dow Jones index finished 1.2 points higher at 10,390.11.
The broader S&P 500 fell 2.7 points to 1,103.25, while the technology-based Nasdaq shed 4.7 points to close at 2,189.61.
In Tokyo shares fell slightly despite promises of a 7.2tn yen ($8.1bn) Government stimulus package to boost the economy.
The main Nikkei 225 index slipped 27.1 points, or 0.3%, to 10,140.47 as analysts remain sceptical the package can aid Japanese economic growth.
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