The FTSE 100 has ended the session down 50.7 points, or 0.78%, to 6,418.7, as miners continued to struggle after copper and gold prices fell heavily overnight.
Vedanta Resources slipped 2.41% to £13.74, closely followed by Kazakhmys which dropped 1.98% to £11.39, while Reckitt Benckiser fell 2.02% to £27.19, and Amvescap declined 2.16% to 587.5p.
However, Legal & General was the biggest loser with a drop of 2.42% to 153.3p, although losses were limited by Kingfisher which advanced 1.03% to end the session at 270.25p.
Brewer Scottish & Newcastle climbed 6.75% to 625p, closely followed by Detica Group which is up 2.17% to 377.5p, while ITV has added 2.16% to 118.4p, and 3I Group climbed 1.23% to £11.48.
In the US, the Dow Jones Industrial Average is down 1.22 points, or 0.01%, to 13,104.28, after a weaker than expected reading on first quarter economic growth.
General Motors is the biggest loser with a fall of 2.13% to $31.76, closely followed by drug company Merck which is down 1.51% to $51.64, while JP Morgan Chase has slipped 1.28% to $52.26.
Pfizer is also down 0.9% to $26.48, while Disney has slipped 0.85% to $34.87, although losses are being limited by Honeywell International which has started the session up 1.01% to $54.23.
Microsoft has posted the biggest gains with a rise of 4.6% to $30.45, closely followed by 3M Company which has climbed 2.14% to 482.17, while Caterpillar has dropped 1.23% to $73.90, and Altria Group is up 0.49% to $69.67.
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