The FTSE 100 has ended the day in the red with a fall of 43.5 points, or 0.7%, to 6,203.9, thanks to a weak mining sector.
Miner Kazakhmys ended the day down 2.65% to £11.38, closely followed by Alliance & Leicester which slipped 2.62% to £11.14, although AstraZeneca was the biggest drag on the index with a fall of 4.4% to £27.38.
DSG International also slipped 2.53% to 192.25p, closely followed by BT Group which fell 2.48% to 305.25p, although losses were limited by Associated British Foods which gained 0.97% to 835p.
Centrica posted the biggest gains with a rise of 2.03% to 352.25p, closely followed by Sage Group which gained 1.33% to 267.5p, while British American Tobacco climbed 1.25% to £14.60, and Persimmon added 1.01% to £15.04.
In the US the Dow Jones Industrial Average is down 10.01 points, or 0.08%, to 12,431.26, as wholesale inflation soared causing concern over the state of the economy.
Home Depot is currently the biggest drag on the index with a fall of 1.23% to $39.47, closely followed by Intel which has slipped 1.21% to $20.59, while AT&T has dropped 0.96% to $35.13.
Caterpillar is also down 0.82% to $61.41, closely followed by American international group which has fallen 0.59% to $72.38, although losses are being limited by Johnson & Johnson which is up 0.53% to $66.95.
However Honeywell International is posting the biggest gains with a rise of 1.69% to $43.95, closely followed by Hewlett-Packard which is up 0.75% to $40.33, while Exxon Mobil has added 0.65% to $76, and Alcoa has climbed 0.59% to $30.60.IFAonline
Clarke replacing Balkham
'Deep-dive analysis of client behaviour'
Ways to mitigate April’s increases
The best equity income funds examined