Early struggles on the FTSE 100 continued throughout the day as the index finished 25.5 points, or 0.39%, on 6524.10.
Mining firm Antofagasta was the biggest loser, finishing down 22 points, or 3.91%, to close on 541p.
It was closely followed by BHP Billiton, one of the morning’s early strugglers, which finished down 44 points, or 3.52%, to £12.05, and Xstrata, which finished down 95 points, or 3.39%, to close on £27.05.
However, it was a positive day for Friends Provident, which finished up 16.25 points, or 8.39%, to close on 210p.
Hammerson, up 105 points, or 6.7%, to close on £16.73, and Ent Inns, up 25 points, or 3.62%, to 715p, also had positive days.
In the US, the Dow Jones slipped a disappointing 125.23 points, or 0.94%, to 13237.64.
Among a sea of red the few winners included IBM, which is up 0.31 points, or 0.3% to 104.69.
But the market was dragged down by some big losers, including Alcoa, down 1 points, or 2.58%, to 37.73.
In addition, Du Pont was down 1.23, or 2.38%, to 50.38. Other losers included Merck, J P Morgan and Caterpillar.
If you would like to comment on this story or speak to its author, telephone Simon Read on 0207 034 2680.IFAonline
Caring for children and elderly relatives
Similar to June 2007
Square Mile’s series of informal interviews
Fine reduced to £60,000
Two roles created