The FTSE 100 has ended the day down 55.2 points, or 0.86%, to 6,357.1 as miners offset gains by financial stocks.
Alliance & Leicester posted the biggest gains with a rise of 7.79% to £11.49, after its results revealed a healthy rise in profit and an increase in mortgage and unsecured lending.
Meanwhile Amvescap climbed 1.73% to 646.5p, closely followed by insurer Old Mutual which gained 1.1% to 183.75p, while Imperial Tobacco Group added 1.85% to £22, and Shire advanced 0.9% to £11.25.
However miners wiped out the gains with Anglo American leading the decline with a fall of 2.54% to £25.36, closely followed by Antofagasta which slipped 1.87% to 473p, while Vodafone dropped 2.33% to 147p, and GlaxoSmithKline fell 1.95% to £14.59.
n the US the Dow Jones Industrial Average is down 64.97 points, or 0.51%, to 12,721.67, following a larger than expected rise in monthly inflation.
Technology stocks are among the biggest fallers with Hewlett-Packard leading the decline with a fall of 4.2% to 441.32, closely followed by Intel which is down 2.12% to $20.74, while General Motors has also slipped 1.42% to $35.44.
Drug company Merck has declined 1.19% to $43.97, while Procter & Gamble has dropped 0.76% to $64.39, although losses are being slightly limited by oil company Exxon Mobil which is up 0.04% to $74.90.
Microsoft is posting the biggest gains with a rise of 0.62% to $29.02, closely followed by McDonald’s which is up 0.61% to $46.08, while Du Pont has added 0.13% to $52.70, and heavy equipment maker Caterpillar has climbed 0.05% to $67.96.IFAonline
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